Optimization and evaluation of venlafaxine hydrochloride fast dissolving oral films
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چکیده
منابع مشابه
Development of Fast Dissolving Sublingual Wafers of Promethazine Hydrochloride
Promethazine hydrochloride, a 5-HT3 antagonist is a powerful antiemetic drug with an oral bioavailability of 25% due to extensive hepatic first pass metabolism and is extremely bitter in taste. To overcome the above draw backs, the present study was carried out to formulate and evaluate fast dissolving taste masked wafers of Promethazine hydrochloride for sublingual administration. Taste maskin...
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Tizanidine HCl is a centrally acting α-2 adrenergic agonist muscle relaxant. It is slightly bitter in taste. In the present study an attempt has been made to prepare bitterless fast dissolving tablet of Tizanidine Hydrochloride using Eudragit E 100 as a taste masking agent. Mass extrusion was the technique used for preparing taste masked granules. The tablet was prepared with three super disint...
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Sertraline Hydrochlride, the selective serotonin reuptake inhibitor (SSRI) is widely used in treatment of depression. Though Sertraline Hydrochloride is well absorbed after oral dosing, there is a first pass metabolism leading to a reduced bioavailability of the drug (44%). Therefore, the present investigation is concerned with the development of Fast Dissolving Tablets of Sertraline Hydrochlor...
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The oral route is most popular route for the administration of therapeutic agents because of the low cost of therapy and ease of administration lead to high levels of patient compliance. The most popular oral solid dosage forms are tablets and capsules. Many patients find it difficult to swallow tablets and hard gelatin capsules particularly pediatric and geriatric patients and do not take thei...
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The hydrochloride of Sertraline is a white crystalline powder; slightly soluble in water and freely soluble in ethanol [1]. It is a drug of selective serotonin reuptake inhibitors (SSRI) that is chemically unrelated to other SSRIs, tricyclic, tetracyclic, or other available antidepressant drugs. Sertraline inhibit the inactivation of serotonin (5hydroxytryptamine or 5-HT) by blocking its absorp...
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ژورنال
عنوان ژورنال: Saudi Pharmaceutical Journal
سال: 2020
ISSN: 1319-0164
DOI: 10.1016/j.jsps.2020.09.001